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aklap
Joined: 02 Oct 2004
Posts: 10520
Location: WI, USA
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 Posted: Sat Oct 14, 2006 4:56 pm Post subject: Overweight in celiac disease (Oct 2006) |
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Overweight in celiac disease: prevalence, clinical characteristics, and effect of a gluten-free diet (Oct 2006).
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17032202&query_hl=1&itool=pubmed_docsum
| Quote: | 1: Am J Gastroenterol. 2006 Oct;101(10):2356-9. Links
Dickey W,
Kearney N.
Departments of Gastroenterology and Dietetics, Altnagelvin Hospital, Londonderry, Northern Ireland, United Kingdom.
BACKGROUND: It is well established that a minority of celiac patients present with "classic" symptoms due to malabsorption. However, few studies have focussed on the distribution of body mass index (BMI) in celiac populations and its relationship to clinical characteristics, or on its response to treatment.
METHODS: We reviewed BMI measurements and other clinical and pathological characteristics from a database of 371 celiac patients diagnosed over a 10-yr period and seen by a single gastroenterologist. To assess response to gluten exclusion, we compared BMI at diagnosis and after 2 yr treatment in patients with serological support for dietary compliance.
RESULTS: Mean BMI was 24.6 kg/m(2) (range 16.3-43.5).
Seventeen patients (5%) were underweight (BMI <18.5),
211 (57%) were normal, and
143 (39%) were overweight (BMI >/=25), including 48 (13% of all patients) in the obese range (BMI >/=30.0).
There was a significant association between low BMI and female gender, history of diarrhea, reduced hemoglobin concentration, reduced bone mineral density (BMD), osteoporosis, and higher grades (subtotal/total) of villous atrophy. Of patients compliant with a gluten-free diet, 81% had gained weight after 2 yr, including 82% of initially overweight patients.
CONCLUSIONS: Few celiac patients are underweight at diagnosis and a large minority is overweight; these are less likely to present with classical features of diarrhea and reduced hemoglobin. Failed or delayed diagnosis of celiac disease may reflect lack of awareness of this large subgroup. The increase in weight of already overweight patients after dietary gluten exclusion is a potential cause of morbidity, and the gluten-free diet as conventionally prescribed needs to be modified accordingly.
PMID: 17032202 [PubMed - in process] |
Yet another study showing underweight is not typical of CD patients. Don't let the docs tell you just because you're overweight that can't have CD!!
I wonder what they mean...
| Quote: | The increase in weight of already overweight patients after dietary gluten exclusion is a potential cause of morbidity, and the gluten-free diet as conventionally prescribed needs to be modified accordingly.
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How would they modified it? Remove the GF junk food?
_________________
Al
“We cannot all do great things, but we can do small things with great love.” Mother Teresa |
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bliss
Joined: 11 Sep 2006
Posts: 15
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| Posted: Thu Nov 02, 2006 12:54 pm Post subject: Re: Overweight in celiac disease (Oct 2006) |
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| aklap wrote: | Overweight in celiac disease: prevalence, clinical characteristics, and effect of a gluten-free diet (Oct 2006).
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17032202&query_hl=1&itool=pubmed_docsum
| Quote: | 1: Am J Gastroenterol. 2006 Oct;101(10):2356-9. Links
Dickey W,
Kearney N.
Departments of Gastroenterology and Dietetics, Altnagelvin Hospital, Londonderry, Northern Ireland, United Kingdom.
BACKGROUND: It is well established that a minority of celiac patients present with "classic" symptoms due to malabsorption. However, few studies have focussed on the distribution of body mass index (BMI) in celiac populations and its relationship to clinical characteristics, or on its response to treatment.
METHODS: We reviewed BMI measurements and other clinical and pathological characteristics from a database of 371 celiac patients diagnosed over a 10-yr period and seen by a single gastroenterologist. To assess response to gluten exclusion, we compared BMI at diagnosis and after 2 yr treatment in patients with serological support for dietary compliance.
RESULTS: Mean BMI was 24.6 kg/m(2) (range 16.3-43.5).
Seventeen patients (5%) were underweight (BMI <18.5),
211 (57%) were normal, and
143 (39%) were overweight (BMI >/=25), including 48 (13% of all patients) in the obese range (BMI >/=30.0).
There was a significant association between low BMI and female gender, history of diarrhea, reduced hemoglobin concentration, reduced bone mineral density (BMD), osteoporosis, and higher grades (subtotal/total) of villous atrophy. Of patients compliant with a gluten-free diet, 81% had gained weight after 2 yr, including 82% of initially overweight patients.
CONCLUSIONS: Few celiac patients are underweight at diagnosis and a large minority is overweight; these are less likely to present with classical features of diarrhea and reduced hemoglobin. Failed or delayed diagnosis of celiac disease may reflect lack of awareness of this large subgroup. The increase in weight of already overweight patients after dietary gluten exclusion is a potential cause of morbidity, and the gluten-free diet as conventionally prescribed needs to be modified accordingly.
PMID: 17032202 [PubMed - in process] |
Yet another study showing underweight is not typical of CD patients. Don't let the docs tell you just because you're overweight that can't have CD!!
I wonder what they mean...
| Quote: | The increase in weight of already overweight patients after dietary gluten exclusion is a potential cause of morbidity, and the gluten-free diet as conventionally prescribed needs to be modified accordingly.
|
How would they modified it? Remove the GF junk food? |
Yes, I think that's exactly what they mean. I've gained nearly 20lbs since going GF, and I was morbidly obese to begin with. I will need to adhere to a low-carb lifestyle in order to lose the weight and prevent additional nutritional deficiencies. |
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