Prevalence of CD in kids with Iron Deficiency (2005)

[aklap]

The prevalence of coeliac disease as detected by screening in children with iron deficiency anaemia. (2005)

Acta Paediatr. 2005 Jun;94(6):678-81. Related Articles, Links

Kalayci AG, Kanber Y, Birinci A, Yildiz L, Albayrak D.

Department of Paediatric Gastroenterology, Ondokuz Mayis University, Samsun, Turkey. ayhangk@omu.edu.tr

AIM: Iron deficiency anaemia is a frequent finding seen in coeliac disease, which can be diagnosed alone or with other findings. In this study, our aim was to determine the prevalence of coeliac disease in children with iron deficiency anaemia without significant gastrointestinal symptoms. METHODS: There were 135 children with iron deficiency anaemia in the patient group (group 1), and 223 healthy children without iron deficiency anaemia in the control group (group 2) in this study. Antiendomysial antibody (EMA) IgA test was given to both groups. Antiendomysial antibody-positive patients underwent small intestine biopsy. RESULTS: The mean age was 7.2+/-4.6 (2-16) y in the patient group (group 1) and 8.2+/-3.8 (2-16) y in the control group (group 2), and no significant difference between the two groups was detected. In terms of gender, there was a significant difference between groups 1 and 2 (M/F: 74/61 and 98/125, respectively) ( p<0.05). EMA was positive in six cases in group 1 (4.4%), and villous atrophy and/or inflammation in the lamina propria with increased intraepithelial lymphocytes was seen on small intestine biopsy in these patients. In the control group, EMA was negative in all children. In detailed histories of patients with coeliac disease diagnosis, recurrent iron deficiency anaemia/pica was found in four patients (66.7%) and occasionally foul-smelling or watery stool attacks were seen in four patients (66.7%). Three of these six patients (50%) had short stature. CONCLUSION: The prevalence of coeliac disease was high in patients with iron deficiency anaemia; therefore, gastrointestinal findings should be further examined for coeliac disease, and the possibility of coeliac disease should be investigated in patients with recurrent iron deficiency anaemia and short stature.

PMID: 16188768 [PubMed - indexed for MEDLINE]
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Al

“We cannot all do great things, but we can do small things with great love.” Mother Teresa

[aklap]

bump for bliss
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Al

“We cannot all do great things, but we can do small things with great love.” Mother Teresa

[Linda]

That's how Ty was diagnosed...his only symptom was anemia.
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Mom of Ty (he's nine) who was diagnosed by bloodwork June 2005, biopsy August 11, 2005, notified on & started GF August 18, 2005