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withdrawal to gluten
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lynda



Joined: 10 Dec 2004
Posts: 170
Location: Hartford,CT

PostPosted: Sun Jan 23, 2005 4:06 pm    Post subject: withdrawal to gluten Reply with quote

i swear i feel like im having withdrawal symptoms from gluten
can this possible be correct????? Crying or Very sad

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LYNDA SmileSmileSmile
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nbmoore7



Joined: 16 Apr 2005
Posts: 2

PostPosted: Sat Apr 16, 2005 3:50 pm    Post subject: Reply with quote

My daughter has been gf for two weeks and I swear that she is having withdraws. It seems that she is having more problems now than before we started the gf lifestyle. Smile
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aklap



Joined: 02 Oct 2004
Posts: 11387
Location: WI, USA

PostPosted: Mon Apr 18, 2005 3:49 pm    Post subject: Reply with quote

Hi NB,

Yes you do go thru withdrawal. Gluten has an opiate effect on your system and you become "addicted". She may feel a bit worse before she feels better. I suspect grumpier too. There all sorts of physical & emotional issue going on. Just try to ride it out the best you can. It does get better Smile
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Al

“We cannot all do great things, but we can do small things with great love.” Mother Teresa
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wendycs



Joined: 16 Apr 2005
Posts: 48
Location: Ontario

PostPosted: Tue Apr 19, 2005 5:46 pm    Post subject: Reply with quote

I went through horrible withdrawls the first couple weeks.. I swear if it weren't for french fries I would have died (ok.. I know.. I'm bad! lol)
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PrtPaty



Joined: 09 Dec 2004
Posts: 65
Location: Oregon

PostPosted: Sun Sep 04, 2005 1:21 pm    Post subject: Re: withdrawl Reply with quote

Al,
Can you point me to any research regarding the "opiate" effect? Or where you heard about it.
thanks,
Patty
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aklap



Joined: 02 Oct 2004
Posts: 11387
Location: WI, USA

PostPosted: Sun Sep 04, 2005 11:12 pm    Post subject: Re: withdrawl Reply with quote

PrtPaty wrote:
Al,
Can you point me to any research regarding the "opiate" effect? Or where you heard about it.
thanks,
Patty

Hi Patty,

Here are a few: I hope this helps!

http://www.findarticles.com/p/articles/mi_m0ISW/is_2002_Dec/ai_94538644

Gluten intolerance, in Autism, is thought to be related to the incomplete digestion and breakdown of proteins. Normally, proteins are digested by enzymes in the intestines and are broken down into long chain amino acids. With maldigestion, short chains of these amino acids, known as peptides, will develop in excess amounts and enter the bloodstream. Peptides from proteins such as gluten and casein, called "exorphins," are biologically active. They interact with opiate receptors in the brain and have the same effects as opiate drugs like heroin and morphine and are also addictive. There are 15 opioid sequences in one molecule of gluten. (13) In fact, the peptides can be up to 30 times more potent than morphine.

The effects of opioids on the body are numerous. (14) "Opioid peptides are key signaling molecules between the endocrine, immune, brain nerve tissues, and the pineal complex, the latter is particularly associated with circadian rhythms." (15) Any abnormal alteration in the quantity of these peptides will have a detrimental effect on all of these systems. Some of the other effects on the body are decreased gastric acid secretion, reduced glutathione levels, immune system depression and modulation of cholecystokinin levels. All of these effects contribute to the inhibition of normal brain, bodily function and growth.

http://www.jbc.org/cgi/reprint/254/7/2446

http://en.wikipedia.org/wiki/Gluten_exorphine

http://www.nationmaster.com/encyclopedia/Gluten

People with celiac disease have a hereditary, genetic predisposition to allergic reaction to gluten in their digestive system and must avoid it entirely. People with autism and autistic spectrum disorders, like Asperger's syndrome, may be sensitive to gluten and casein (a protein in milk); both seem to have an opiate-like effect on these people. The opioid effect of gluten is caused by gluten exorphines and gliadorphin. These are peptides formed in the digestion of gluten. See more at gluten-free, casein-free diet. Another condition which may cause one to follow a gluten-free diet is dermatitis herpetiformis.


http://www.glutenfree.com/autism.htm
These opiates are highly addictive and can reach toxic levels. A chemical dependency may develop that makes it difficult to “quit” eating foods containing these substances. This may be a possible explanation as to why many children with Autism crave milk and wheat products.



While I have not read this book, it is a highly recommended book by others.
Below is from the book "Dangerous Grains" by Ron Hoggan

The addictive nature of gluten is often overlooked. For some, the first days and weeks of following a gluten-free diet are characterized by food cravings, disorientation, irritability, sleepiness, depression, mental fogginess, fatigue, and/or shortness of breath. If you are a member of this group, the very fact that you are experiencing many of these symptoms should reinforce the need to exclude gluten from your diet. These are common symptoms of withdrawl of detoxification from gluten-derived opiods and brain neurochemical imbalances. The evidence suggests that about 70 percent of celiac patients will experience these symptoms when beginning a strict gluten-free diet.

...

Most individuals who have celiac disease or non-celiac gluten sensitivity are also addicted to gluten. The morphine-like peptides from gluten frequently stay intact because the bonds between some sequences amino acids are quite resistant to digestion. Those who have leaky gut will allow these opioids and other large peptides to enter the bloodstream. The addictive process has probably been at work in most gluten-sensitive and celiac individuals for many years, probably since childhood. This makes elimination of gluten a great deal more challenging than might be expected.


http://www.absoluteastronomy.com/encyclopedia/g/gl/gluten-free,_casein-free_diet.htm
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Al

“We cannot all do great things, but we can do small things with great love.” Mother Teresa
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jayhawkmom



Joined: 19 Apr 2006
Posts: 851
Location: Midwest, USA

PostPosted: Sat Jun 17, 2006 12:41 pm    Post subject: Reply with quote

I am SO glad to read this!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

My daughter is acting WORSE now than she was before. She's just crazed, almost, it seems. Granted, she did have an accidental gluten incident the other day, but she's really bonkers, and intolerable right now. Perhaps she is going through withdrawl as well.
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Noatak



Joined: 13 Nov 2005
Posts: 497
Location: Massachusetts

PostPosted: Sat Jun 17, 2006 5:15 pm    Post subject: Reply with quote

I think anything you've become used to eating for a long time will be missed and withdrawal suffered when it goes completely from your system. It's the same mechanism as things like smoking....gluten gave a pleasureable feeling because it's wrapped up in all the goodies we like to eat. Emotional food.

I treated myself to GF goodies at first not only because I could eat them without feeling horrible but it was a kind of replacement for the things I could no longer eat. It helped. So mix up a batch of GF brownies or cookies and dig in! Laughing

On a positive note....most of the bad withdrawal goes after 2-3 weeks and it gets better all the time after that.
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aklap



Joined: 02 Oct 2004
Posts: 11387
Location: WI, USA

PostPosted: Sun Jul 23, 2006 9:00 pm    Post subject: Reply with quote

bump for Noah's Wife
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Al

“We cannot all do great things, but we can do small things with great love.” Mother Teresa
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Fidissimus



Joined: 17 Mar 2006
Posts: 2073
Location: Portland, OR.

PostPosted: Mon Jul 24, 2006 1:02 am    Post subject: Reply with quote

Noatak wrote:
I treated myself to GF goodies at first not only because I could eat them without feeling horrible but it was a kind of replacement for the things I could no longer eat. It helped. So mix up a batch of GF brownies or cookies and dig in! Laughing


Just don't forget to quit the goodies eventually... like some of us! Laughing

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Jenn

GF BD: Feb. 2001
Free of wheat, barley, rye, oats, dairy, eggs, almonds, pineapple and brewers yeast.
http://graindamaged.blogspot.com/
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aklap



Joined: 02 Oct 2004
Posts: 11387
Location: WI, USA

PostPosted: Thu Mar 12, 2009 12:40 pm    Post subject: Reply with quote

Someone posted this on GFAB. Here's an older blog entry from Dr. Charles Parker that discusses it. He too quotes Ron Hoggan, author of Dangerous Grains Wink.

This very thread was linked in his blog entry. Cool

http://www.corepsychblog.com/2007/08/celiac-notes-opiate-withdrawal-from-gluten-and-casein/
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Al

“We cannot all do great things, but we can do small things with great love.” Mother Teresa
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aklap



Joined: 02 Oct 2004
Posts: 11387
Location: WI, USA

PostPosted: Sun Jul 26, 2009 10:14 am    Post subject: Reply with quote

bump for LynnHopes
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Al

“We cannot all do great things, but we can do small things with great love.” Mother Teresa
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crampygut



Joined: 04 Aug 2009
Posts: 13
Location: Australia

PostPosted: Wed Aug 05, 2009 6:11 pm    Post subject: Gluten Withdrawals--- please help ????? Reply with quote

Hi gang, this is my first post and I really am reaching out for some very valuable and desperate information. I was recently diagnosed with a strong Gluten Intolerance and so I started a gluten free diet two weeks ago. I am a 38 year old male who already has Crohn's disease. For the past two weeks my life has been a kind of hell. I have been randomly depressed, anxiety, brain fog and general lack of interest in everything. I have read this can be caused by symptoms of stopping gluten but thought, maybe because I did have these symptoms to a much much lesser degree before the diet, it is just a coincidence and that these symptoms were bound to get worse even if I wasn't on the diet? Has anyone experienced these symptoms when starting this diet and if so how long does it usually last????? Sad

Kind regards
Michael
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Michael

Crohn's disease since 2005.
Gluten free diet since August 2009.
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smalltownslackermom



Joined: 04 May 2009
Posts: 363
Location: mid north american continent

PostPosted: Thu Aug 06, 2009 8:39 am    Post subject: Reply with quote

My son and I show roughly a 6 weeks withdrawal pattern. and while our systems are definitely NOT all perfect after that, that seems to clear the worst of the brain/neuro/psych effects.
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son - high ttg - 4/09, pos. biopsy 5/09
self - negative bloodwork 5/09, pos. biopsy 11/09
sister - gf for ~3 years and is a new person
niece - positive ttg 2/10, foregoing biopsy


Last edited by smalltownslackermom on Sat Aug 08, 2009 10:55 am; edited 1 time in total
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crampygut



Joined: 04 Aug 2009
Posts: 13
Location: Australia

PostPosted: Thu Aug 06, 2009 8:32 pm    Post subject: Reply with quote

Thank you for your reply smalltownslackermom, did you have the same kind of psych symptoms during the 6 weeks as well? and were they pretty intense?
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Michael

Crohn's disease since 2005.
Gluten free diet since August 2009.
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